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How Does Cell Density Measurement Work?
Many parameters like pH and dissolved oxygen can be monitored in-line but those directly related to cell physiology are typically time consuming offline measurements that require many manual steps. Total and Viable Cell Density measurement is now possible in-line with a new breed of sensors. Learn more about saving time and effort and increasing productivity and process understanding with in-line cell density sensors in the video below.
Viable Cell Density Sensors
Incyte Arc sensors provide a means for directly measuring viable cell density in real-time, meeting the increasing need for PAT in the biopharmaceutical industry. Clear, instantly available information ensures critical events that could have been missed between off-line samples are now immediately recognizable.
Total Cell Density Sensors
Total cell density measurement by the Dencytee sensor is based on optical density, commonly known as the turbidity of a suspension at near-infrared (NIR) wavelengths. All particles and molecules that scatter the NIR light will be detected. This optical density signal can be correlated to the total cell density measured by different offline measurement techniques.